Includes bibliographical references and index.

Bioinformatics challenges for the geneticist / Michael R. Barnes -- Managing and manipulating genetic data / Karl W. Broman and Simon C. Heath -- The HapMap: a haplotype map of the human genome / Ellen M. Brown and Bryan J. Barratt -- Assembling a view of the human genome / Colin A.M. Semple -- Finding, delineating and analysing genes / Christopher D. Southan and Michael R. Barnes -- Comparative genomics / Martin S. Taylor and Richard R. Copley -- Identifying mutations in single-gene disorders / David P. Kelsell, Diana Blaydon, and Charles A. Mein -- From genome scan to culprit gene: refining loci implicated by genome scans / Ian C. Gray -- Integrating genetics, genomics and epigenomics to identify disease genes / Michael R. Barnes -- Tools for statistical analysis of genetic data / Aruna Bansal, Charlotte Vignal, and Ralph McGinnis -- Predictive functional analysis of polymorphisms: an overview / Mary Plumpton and Michael R. Barnes -- Functional in silico analysis of gene regulatory polymorphism / Chaolin Zhang, Xiaoyue Zhao, and Michael Q. Zhang -- Amino-acid properties and consequences of substitutions / Matthew J. Betts and Robert B. Russell -- Non-coding RNA bioinformatics / James Brown ... [et al.] -- What are microarrays?: an introduction to microarray methods for measuring the iranscriptome / Catherine A. Ball and Gavin Sherlock -- Combining quantitative traits and gene-expression data / Elissa J. Chesler -- Bioinformatics and cancer genetics / Joel Greshock -- Needle in a haystack?: dealing with 500 000 SNP genome scans / Michael R. Barnes and Paul S. Derwent -- A bioinformatics perspective on genetics in drug discovery and development / Christopher D. Southan, Magnus Ulvsback, and Michael R. Barnes.