TY  - BOOK
AU  - Feldman,David
AU  - Pike,J.Wesley
AU  - Adams,John S.
TI  - Vitamin D
SN  - 9780123819789
AV  - QP772.V53 V572 2011
PY  - 2011///
CY  - Amsterdam, Boston
PB  - Academic Press
KW  - Vitamin D
KW  - fast
N1  - "Elsevier science & technology books"--Page facing title page; Includes bibliographical references and index; Volume I: Section I: Chemistry, metabolism, circulation -- Historical overview of vitamin D / Hector F. Deluca -- Photobiology of vitamin D / Michael F. Holick -- The activating enzymes of vitamin D metabolism (25- and 1a-hydroxylases) / Glenville Jones and David E. Prosser -- CYP24A1: Structure, function, and physiological role / Rene St. Arnaud -- The vitamin D binding protein DBP / Roger Bouillon -- Industrial aspects of vitamin D / Arnold Lippert Hirsch; Volume I: Section II: Mechanisms of action -- The vitamind D receptor: Biochemical, molecular, biological, and genomic era investigations / J. Wesley Pike, Mark B. Meyer, and Seong Min Lee -- Nuclear vitamin D receptor: Natural ligands, molecular structure-function, and transcriptional control of vital genes / Mark R. Haussler, G. Kerr Whitfield, Carol A. Haussler, Jui-Cheng Hsieh, and Peter W. Jurutka -- Structural basis for ligand activity in VDR / Natacha Rochel and Dino Moras -- Coregulators of VDR-mediated gene expression / Diane R. Dowd and Paul N. McDonald -- Target genes of vitamin D: Spatio-temporal interaction of chromatin, VDR, and response elements / Carsten Carlberg -- Epigenetic modifications in vitamin D receptor-mediated transrepression / Alexander Kouzmenko, Fumiaki Ohtake, Ryoji Fujiki, and Shigeaki Kato -- Vitamin D and Wnt/ß-catenin signaling / José Manuel González-Sancho, María Jesûs Larriba, and Albert Munoz -- Vitamin D response element-binding protein / Thomas S. Lisse, Hong Chen, Mark S. Nanes, Martin Hewison, and John S. Adams -- Vitamin D sterol/VDR conformational dynamics and nongenomic actions / Mathew T. Mizwicki and Anthony W. Norman; Volume I: Section III: Mineral and bone homeostasis -- Development of the skeleton / Jane B. Lian, Gary S. Stein, Martin Montecino, Janet L. Stein, and Andre J. van Wijnen -- Vitamin D regulation of osteoblast function / Renny Franchesci and Yan Li -- Osteoclasts / F. Patrick Ross -- Molecular mechanisms for regulation of intestinal calcium and phosphate absorption by vitamin D / James Fleet and Ryan D. Schoch -- The calbindins: Calbindin-D28K and calbindin-D9K and the epithelial calcium channels TRPV5 and TRPV6 / Sylvia Christakos, Leila Mady, and Puneet Dhawan -- Mineralization / Eve Donnelly and Adele L. Boskey -- Vitamin D regulation of type I collagen expression in bone / Barbara Kream and Alexander Lichtler -- Target genes: Bone proteins / Gerald J. Atkins, David M. Findlay, Paul H. Anderson, and Howard A. Morris -- Vitamin D and the calcium-sensing receptor / Edward M. Brown -- Effects of 1,25-dihydroxyvitamin D3 on voltage-sensitive calcium channels in osteoblast differentiation and morphology / William R. Thompson and Mary Farach-Carson; Volume I: Section IV: Targets -- Vitamin D and the kidney / Peter Tebben and Rajiv Kumar -- Vitamin D and the parathyroids / Justin Silver and Tally Neveh-Many -- Cartilage / Barbara D. Boyan, Maryam Doroudi and Zvi Schwartz -- Vitamin D and oral health / Ariane Berdal, Muriel Molla, and Vianney Descroix -- The role of vitamin D and its receptor in skin and hair follicle biology / Marie B. Demay -- Vitamin D and the cardiovascular system / David Gardner, Songcang Chen, Denis Glenn, and Wei Ni -- Vitamin D: A neurosteroid affecting brain development and function; Implications for neurological and psychiatric disorders / Darryl Eyles, Thomas Burne, and John McGrath -- Contributions of genetically modified mouse models to understanding the physiology and pathophysiology of the 25-hydroxyvitamin D-1-alpha hydroxylase enzyme [1a(OH)ase] and the vitamin D receptor (VDR) / Geoffrey N. Hendy, Richard Kremer, and David Goltzman; Volume I: Section V: Human physiology -- Vitamin D: Role in the calcium and phosphorus economies / Robert P. Heaney -- Fetus, neonate and infant / Chris Kovacs -- Vitamin D deficiency and calcium absorption during childhood / Steven A. Abrams -- Adolescence and acquisition of peak bone mass / Connie Weaver, Rick Lewis, and Emma Liang -- Vitamin D metabolism in pregnancy and lactation / Natalie W. Thiex, Heidi J. Kalkwarf, and Bonnie L. Specker -- Vitamin D: Relevance in reproductive biology and pathophysiological implications in reproductive dysfunction / Lubna Pal and Hugh S. Taylor -- Vitamin D and the renin-angiotensin system / Yan Chun Li -- Parathyroid hormone, parathyroid hormone-related protein and calcitonin / Elizabeth Holt and John J. Wysolmerski -- FGF23/Klotho new regulators of vitamin D metabolism / Valentin David and L. Darryl Quarles -- The role of the vitamin D receptor in bile acid homeostasis / Daniel R. Schmidt, Steven A. Kliewer, and David J. Mangelsdorf -- Vitamin D and fat / Francisco J.A. de Paula and Clifford J. Rosen -- Extrarenal 1a-hydroxylase / Martin Hewison and John S. Adams; Volume I: Section VI: Diagnosis and management -- Approach to the patient with metabolic bone disease / Michael P. Whyte -- Detection of vitamin D and its major metabolites / Bruce W. Hollis -- Bone histomorphometry / Linda Skingle and Juliet Compston -- Radiology of rickets and osteomalacia / Judith E. Adams -- High-resolution imaging techniques for bone quality assessment / Andrew J. Burghardt, Roland Krug, and Sharmila Majumdar -- The role of vitamin D in orthopaedic surgery / Aasis Unnanuntana, Brian J. Rebolledo, and Joseph M. Lane; Volume I: Section VII: Nutrition, sunlight, genetics and vitamin D deficiency -- Worldwide vitamin D status / Paul Lips and Natasja van Schoor -- Sunlight, vitamin D and prostate cancer epidemiology / Gary G. Schwartz -- Nutrition and lifestyle effects on vitamin D status / Susan J. Whiting and Mona S. Calvo -- Bone loss, vitamin D and bariatric surgery: Nutrition and obesity / Lenore Arab and Ian Yip -- Genetics of the vitamin D endocrine system / André G. Uitterlinden -- The pharmacology of vitamin D / Reinhold Vieth -- How to define optimal vitamin D status / Roger Bouillon; Volume II: Section VIII: Disorders -- The hypocalcemic disorders: Differential diagnosis and therapeutic use of vitamin D / Thomas O. Carpenter and Karl L. Insogna -- Vitamin D deficiency and nutritional rickets in children / John M. Pettifor -- Vitamin D and osteoporosis / Peter R. Ebeling and John A. Eisman -- Relevance of vitamin D deficiency in adult fracture and fall prevention / Heike Bischoff-Ferrari and Bess Dawson-Hughes -- Clinical disorders of phosphate homeostasis / Karen E. Hansen and Marc K. Drezner -- Pseudo-vitamin D deficiency / Francis H. Glorieux, Thomas Edouard, and René St-Arnaud -- Hereditary 1,25-dihydroxyvitamin-D-resistant rickets / Peter J. Malloy, Dov Tiosano, and David Feldman -- Glucocorticoids and vitamin D / Philip Sambrook -- Drug and hormone effects on vitamin D metabolism / Barrie M. Weinstein and Sol Epstein -- Vitamin D and organ transplantation / Emily M. Stein and Elizabeth Shane -- Vitamin D and bone mineral metabolism in hepatogastrointestinal diseases / Daniel Bikle -- Vitamin D and renal disease / Adriana S. Dusso and Eduardo Slatopolsky -- Idiopathic hypercalciuria and nephrolithiasis / Murray J. Favus and Fredric L. Coe -- Hypercalcemia due to vitamin D toxicity / Natalie E. Cusano, Susan Thys-Jacobs, and John P. Bilezikian -- Vitamin D: Cardiovascular effects and vascular calcification / Dwight A. Towler; Volume II: Section IX: Analogs -- Alterations in 1,25-dihydroxyvitamin D3 structure that produce profound changes in in Vivo activity / Hector DeLuca and Lori A. Plum -- Mechanisms for the selective actions of vitamin D analogs / Alex J. Brown -- Analogs of calcitriol / Lieve Verlinden, Guy Eelen, Roger Bouillon, Maurits Vandewalle, Pierre De Clercq, and Annemieke Verstuyf -- Analogs for the treatment of osteoporosis / Noboru Kubodera and Fumiaki Takahashi -- Non-secosteroidal ligands and modulators / Keith R. Stayrook, Matthew W. Carson, Yanfei L. Ma, and Jeffrey A. Dodge -- The bile acid derivatives lithocholic acid acetate and lithocholic acid propionate are functionally selective vitamin D receptor ligands / Makoto Makishima and Sachiko Yamada -- CYP24A1 regulation in health and disease / Martin Petkovich, Christian Helvig, and Tina Epps -- Calcitriol and analogs in the treatment of chronic kidney disease / Ishir Bhan and Ravi Thadhani; Volume II: Section X: Cancer -- The epidemiology of vitamin D and cancer risk / Edward Giovannucci -- Vitamin D: Cancer and differentiation / Johannes P.T.M. van Leeuwen, Marjolein van Driel, David Feldman, and Alberto Munoz -- Vitamin D effects on differentiation and cell cycle / George P. Studzinski, Elzbieta Gocek, and Michael Danilenko -- Vitamin D actions in mammary gland and breast cancer / JoEllen Welsh -- Vitamin D and prostate cancer / Aruna V. Krishnan and David Feldman -- The vitamin D system and colorectal cancer prevention / Heide S. Cross -- Hematological malignancy / Ryoko Okamoto and H. Phillip Koeffler -- Vitamin D and skin cancer / Jean Y. Tang and Ervin H. Epstein, Jr. -- The anti-tumor effects of vitamin D in other cancers / Donald L. Trump and Candace S. Johnson; Volume II: Section XI: Immunity, inflammation, and disease -- Vitamin D and innate immunity / John H. White -- Control of adaptive immunity by vitamin D receptor agonists / Luciano Adorini -- The role of vitamin D in innate immunity: Antimicrobial activity, oxidative stress and barrier function / Philip T. Liu -- Vitamin D and diabetes / Conny Gysemans, Hannelie Korf, and Chantal Mathieu -- Vitamin D and multiple sclerosis / Colleen E. Hayes, Faye E. Nashold, Christopher G. Mayne, Justin A. Spanier, and Corwin D. Nelson -- Vitamin D and inflammatory bowel disease / Danny Bruce and Margherita T. Cantorna -- Psoriasis and other skin diseases / Jörg Reichrath and Michael F. Holick; Volume II: Section XII: Therapeutic applications and new advances -- The role of vitamin D in type 2 diabetes and hypertension / Anastassios G. Pittas and Bess Dawson-Hughes -- Vitamin D receptor agonists in the treatment of benign prostatic hyperplasia / Annamaria Morelli, Mario Maggi, and Luciano Adorini -- Sunlight protection by vitamin D compounds / Rebecca S. Mason, Katie M. Dixon, Vanessa B. Sequiera, and Clare Gordon-Thomson -- The role of vitamin D in osteoarthritis and rheumatic disease / M. Kyla Shea and Timothy M. McAlindon -- Vitamin D and cardiovascular disease / Harald Sourij and Harald Dobnig -- Vitamin D, childhood wheezing, asthma, and chronic obstructive pulmonary disease / Carlos A. Camargo Jr., Adit Ginde, and Jonathan Mansbach -- Vitamin D and skeletal muscle function / Lisa Ceglia and Robert U. Simpson -- The VITamin D and omegA-3 TriaL (VITAL): Rationale and design of a large-scale randomized controlled trial / Olivia I. Okereke and JoAnn E. Manson
N2  - Vitamin D, a steroid hormone, has primarily been known for its effects on bone and osteoporosis. Current therapeutic practices have expanded into such fields as cancer research, pediatrics, nephrology, dermatology, immunology, and genetics. This edition covers Vitamin D's chemistry, metabolism, mechanisms of action, diagnosis and management, new analogs, and emerging therapies
ER  -